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Sfoglia per Autore "Koromila, T."

Items 1-9 di 9

    • Assessment of gene-by-sex interaction effect on bone mineral density 

      Liu, C. T.; Estrada, K.; Yerges-Armstrong, L. M.; Amin, N.; Evangelou, E.; Li, G.; Minster, R. L.; Carless, M. A.; Kammerer, C. M.; Oei, L.; Zhou, Y. H.; Alonso, N.; Dailiana, Z.; Eriksson, J.; Garcia-Giralt, N.; Giroux, S.; Husted, L. B.; Khusainova, R. I.; Koromila, T.; Kung, A. W.; Lewis, J. R.; Masi, L.; Mencej-Bedrac, S.; Nogues, X.; Patel, M. S.; Prezelj, J.; Richards, J. B.; Sham, P. C.; Spector, T.; Vandenput, L.; Xiao, S. M.; Zheng, H. F.; Zhu, K.; Balcells, S.; Brandi, M. L.; Frost, M.; Goltzman, D.; Gonzalez-Macias, J.; Karlsson, M.; Khusnutdinova, E. K.; Kollia, P.; Langdahl, B. L.; Ljunggren, O.; Lorentzon, M.; Marc, J.; Mellstroem, D.; Ohlsson, C.; Olmos, J. M.; Ralston, S. H.; Riancho, J. A.; Rousseau, F.; Urreizti, R.; Van Hul, W.; Zarrabeitia, M. T.; Castano-Betancourt, M.; Demissie, S.; Grundberg, E.; Herrera, L.; Kwan, T.; Medina-Gomez, C.; Pastinen, T.; Sigurdsson, G.; Thorleifsson, G.; VanMeurs, J. B. J.; Blangero, J.; Hofman, A.; Liu, Y. M.; Mitchell, B. D.; O'Connell, J. R.; Oostra, B. A.; Rotter, J. I.; Stefansson, K.; Streeten, E. A.; Styrkarsdottir, U.; Thorsteinsdottir, U.; Tylavsky, F. A.; Uitterlinden, A.; Cauley, J. A.; Harris, T. B.; Ioannidis, J. P. A.; Psaty, B. M.; Robbins, J. A.; Zillikens, M. C.; VanDuijn, C. M.; Prince, R. L.; Karasik, D.; Rivadeneira, F.; Kiel, D. P.; Cupples, L. A.; Hsu, Y. H. (2012)
      Sexual dimorphism in various bone phenotypes, including bone mineral density (BMD), is widely observed; however, the extent to which genes explain these sex differences is unclear. To identify variants with different effects ...

    • Bone morphogenetic protein mRNA expression in human periosteum during fracture healing 

      Chassanidis, C. G.; Samara, S.; Koromila, T.; Varitimidis, S.; Dailiana, Z.; Malizos, K.; Kollia, P. (2008)

    • Bone morphogenetic proteins (BMPs) expression in the femoral heads of patients with avascular necrosis 

      Samara, S.; Dailiana, Z.; Varitimidis, S.; Chassanidis, C.; Koromila, T.; Malizos, K. N.; Kollia, P. (2013)
      Avascular necrosis (AVN) is a disorder of the bone repair process which usually results in femoral head (FH) destruction. Bone morphogenetic proteins (BMPs) are the key proteins regulating bone remodelling and healing. ...

    • CER1 gene variations associated with bone mineral density, bone markers, and early menopause in postmenopausal women 

      Koromila, T.; Georgoulias, P.; Dailiana, Z.; Ntzani, E. E.; Samara, S.; Chassanidis, C.; Aleporou-Marinou, V.; Kollia, P. (2013)
      Background: Osteoporosis has a multifactorial pathogenesis characterized by a combination of low bone mass and increased fragility. In our study, we focused on the effects of polymorphisms in CER1 and DKK1 genes, recently ...

    • Expression profile of osteoprotegerin, RANK and RANKL genes in the femoral head of patients with avascular necrosis 

      Samara, S.; Dailiana, Z.; Chassanidis, C.; Koromila, T.; Papatheodorou, L.; Malizos, K. N.; Kollia, P. (2014)
      Introduction: Femoral head avascular necrosis (AVN) is a recalcitrant disease of the hip that leads to joint destruction. Osteoprotegerin (OPG), Receptor Activator of Nuclear Factor kappa-B (RANK) and RANK ligand (RANKL) ...

    • Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture 

      Estrada, K.; Styrkarsdottir, U.; Evangelou, E.; Hsu, Y. H.; Duncan, E. L.; Ntzani, E. E.; Oei, L.; Albagha, O. M. E.; Amin, N.; Kemp, J. P.; Koller, D. L.; Li, G.; Liu, C. T.; Minster, R. L.; Moayyeri, A.; Vandenput, L.; Willner, D.; Xiao, S. M.; Yerges-Armstrong, L. M.; Zheng, H. F.; Alonso, N.; Eriksson, J.; Kammerer, C. M.; Kaptoge, S. K.; Leo, P. J.; Thorleifsson, G.; Wilson, S. G.; Wilson, J. F.; Aalto, V.; Alen, M.; Aragaki, A. K.; Aspelund, T.; Center, J. R.; Dailiana, Z.; Duggan, D. J.; Garcia, M.; Garcia-Giralt, N.; Giroux, S.; Hallmans, G.; Hocking, L. J.; Husted, L. B.; Jameson, K. A.; Khusainova, R.; Kim, G. S.; Kooperberg, C.; Koromila, T.; Kruk, M.; Laaksonen, M.; Lacroix, A. Z.; Lee, S. H.; Leung, P. C.; Lewis, J. R.; Masi, L.; Mencej-Bedrac, S.; Nguyen, T. V.; Nogues, X.; Patel, M. S.; Prezelj, J.; Rose, L. M.; Scollen, S.; Siggeirsdottir, K.; Smith, A. V.; Svensson, O.; Trompet, S.; Trummer, O.; van Schoor, N. M.; Woo, J.; Zhu, K.; Balcells, S.; Brandi, M. L.; Buckley, B. M.; Cheng, S. L.; Christiansen, C.; Cooper, C.; Dedoussis, G.; Ford, I.; Frost, M.; Goltzman, D.; Gonzalez-Macias, J.; Kahonen, M.; Karlsson, M.; Khusnutdinova, E.; Koh, J. M.; Kollia, P.; Langdahl, B. L.; Leslie, W. D.; Lips, P.; Ljunggren, O.; Lorenc, R. S.; Marc, J.; Mellstrom, D.; Obermayer-Pietsch, B.; Olmos, J. M.; Pettersson-Kymmer, U.; Reid, D. M.; Riancho, J. A.; Ridker, P. M.; Rousseau, F.; Slagboom, P. E.; Tang, N. L. S.; Urreizti, R.; Van Hul, W.; Viikari, J.; Zarrabeitia, M. T.; Aulchenko, Y. S.; Castano-Betancourt, M.; Grundberg, E.; Herrera, L.; Ingvarsson, T.; Johannsdottir, H.; Kwan, T.; Li, R.; Luben, R.; Medina-Gomez, C.; Palsson, S. T.; Reppe, S.; Rotter, J. I.; Sigurdsson, G.; van Meurs, J. B. J.; Verlaan, D.; Williams, F. M. K.; Wood, A. R.; Zhou, Y. H.; Gautvik, K. M.; Pastinen, T.; Raychaudhuri, S.; Cauley, J. A.; Chasman, D. I.; Clark, G. R.; Cummings, S. R.; Danoy, P.; Dennison, E. M.; Eastell, R.; Eisman, J. A.; Gudnason, V.; Hofman, A.; Jackson, R. D.; Jones, G.; Jukema, J. W.; Khaw, K. T.; Lehtimaki, T.; Liu, Y. M.; Lorentzon, M.; McCloskey, E.; Mitchell, B. D.; Nandakumar, K.; Nicholson, G. C.; Oostra, B. A.; Peacock, M.; Pols, H. A. P.; Prince, R. L.; Raitakari, O.; Reid, I. R.; Robbins, J.; Sambrook, P. N.; Sham, P. C.; Shuldiner, A. R.; Tylavsky, F. A.; van Duijn, C. M.; Wareham, N. J.; Cupples, L. A.; Econs, M. J.; Evans, D. M.; Harris, T. B.; Kung, A. W. C.; Psaty, B. M.; Reeve, J.; Spector, T. D.; Streeten, E. A.; Zillikens, M. C.; Thorsteinsdottir, U.; Ohlsson, C.; Karasik, D.; Richards, J. B.; Brown, M. A.; Stefansson, K.; Uitterlinden, A. G.; Ralston, S. H.; Ioannidis, J. P. A.; Kiel, D. P.; Rivadeneira, F. (2012)
      Bone mineral density (BMD) is the most widely used predictor of fracture risk. We performed the largest meta-analysis to date on lumbar spine and femoral neck BMD, including 17 genome-wide association studies and 32,961 ...

    • Novel Sequence Variations in the CER1 Gene Are Strongly Associated with Low Bone Mineral Density and Risk of Osteoporotic Fracture in Postmenopausal Women 

      Koromila, T.; Dailiana, Z.; Samara, S.; Chassanidis, C.; Tzavara, C.; Patrinos, G. P.; Aleporou-Marinou, V.; Kollia, P. (2012)
      Osteoporosis is a common skeletal disease characterized by a combination of low bone mass and increased fragility. In this case-control study, we investigated the possible association of two novel candidate genes, CER1 and ...

    • Predictive role of cytokine gene polymorphisms for the development of femoral head osteonecrosis 

      Samara, S.; Kollia, P.; Dailiana, Z.; Chassanidis, C.; Papatheodorou, L.; Koromila, T.; Malizos, K. N. (2012)
      Introduction: Osteonecrosis (ON) is a multifactorial disease that leads to hip destruction. Lately, much focus has been at femoral head preservation with nonsurgical methods. In this study we examined the polymorphisms of ...

    • Smoking affects mRNA expression of bone morphogenetic proteins in human periosteum 

      Chassanidis, C. G.; Malizos, K. N.; Varitimidis, S.; Samara, S.; Koromila, T.; Kollia, P.; Dailiana, Z. (2012)
      Periosteum is important for bone homoeostasis through the release of bone morphogenetic proteins (BMPs) and their effect on osteoprogenitor cells. Smoking has an adverse effect on fracture healing and bone regeneration. ...